![]() ![]() The most frequent adverse effects in the H2O2 group were a burning throat and nose. Among family members, 86.0% had no antibodies, 2.3% had antibodies, and 11.6% had active infections (4 in the experimental group and 6 in the control group). ![]() The symptom of dyspnea presented a significant difference between days 2 and 4 (p<0.05). The most frequent symptoms on day 0 were cough, loss of taste, and hyposmia there were no significant differences between groups, independent of the period. An average post-treatment interval of 8 days passed before testing family members. The researchers contacted patients every 2 days over an 8-day period. Family members received the same treatment as the treated COVID-19 patient. Patients gargled the solution 3 times a day, and applied the nasal spray twice a day, for a 7-day period. Patients positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), who were treated in a hospital or at home, and patients' family members (not positive for SARS-CoV-2), were randomized into 2 groups: experimental (1% H2O2 for gargling, 0.5% H2O2 for nasal wash), and control. This study evaluated the effectiveness of hydrogen peroxide (H2O2) as mouthwash and nasal spray on symptom relief in coronavirus disease 2019 (COVID-19) patients. ![]()
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